Clinical Study

APPROVED FOR A CLINICAL STUDY

Connexus®

Brain-Computer Interface

The first high-data-rate BCI designed for long-term medical use

Our Purpose

Recapturing what the brain never forgot

Communication is a fundamental human need. For people living with motor conditions caused by ALS, spinal cord injury, or stroke, the loss of speech and motor functionality can isolate them from the world.

At Paradromics, we're building a future where motor impairment no longer means silence or disconnection. Our Connexus Brain-Computer Interface (BCI) is designed to transform neural signals into communication – synthesized speech, text, and computer control – at speeds that enable natural conversations.

Introducing Connexus BCI

Designed for data rate, safety, and durability

This is advanced neurotechnology built on 30 years of brain-machine interface research, refined through relentless engineering, and designed for long-term medical use.

This is Connexus BCI.

The data difference

421 microelectrodes, each smaller than a human hair, reach 1.5mm below the brain's surface to capture signals from individual neurons as they fire. This level of resolution enables a clear picture of the user's intended action. In pre-clinical testing, the Connexus BCI demonstrated an information transfer rate exceeding 200 bits per second (bps) – 20x faster than existing BCIs.

Safety by design

Every component within the Connexus BCI was thoughtfully selected to avoid risk. It uses medically proven materials and packaging technology and is implanted using surgical steps that are already familiar to nearly every neurosurgeon. The Connexus BCI is designed to deliver the safest possible path from development to patient use.

Built to last

The Connexus BCI is a fully internalized, fully wireless system. It is hermetically sealed against moisture to protect it from the body. Every design choice prioritizes longevity because every BCI user deserves a device that is engineered to last as long as needed. The goal is stable neural recordings for more than 10 years.

how it works

From neural signals to natural speech

01

Surgical placement

A neurosurgeon places three components beneath the skin: the brain interface, a chest transceiver, and a flexible connector. The procedure uses established neurosurgical techniques refined over decades in other health care applications.
02

neural signal capture

Our brain interface's microelectrodes extend just beneath the brain's surface, recording electrical activity directly from individual neurons in the motor cortex.
03

wireless transmission

Data flows through the flexible lead to the chest transceiver, which transmits information via a secure near-infrared optical link to an external transceiver worn by the user. That external device also powers the entire system through inductive power – the same technology that charges smartphones wirelessly.
04

ai-powered translation

A portable computer running advanced language models and neural decoding algorithms receives the data. Machine learning analyzes neural patterns to determine what the user intends to communicate or control, then translates those intentions into synthesized speech, screen text, or computer commands.
*Connexus BCI is an investigational device limited by United States law to investigational use.
*Connexus BCI is an investigational device limited by United States law to investigational use.
*Connexus BCI is an investigational device limited by United States law to investigational use.
*Connexus BCI is an investigational device limited by United States law to investigational use.

Clinical Study Begins 2026

Advancing the science of speech decoding and restoration

The Connect-One Clinical Study is testing the Connexus BCI's capabilities to restore communication for people who can no longer speak.

Participants can help shape a future where they – and countless others – can communicate, use a computer, and live more independently.